Evidence in Practice
Spironolactone is more effective at lowering blood pressure than bisoprolol or doxazosin in people with resistant hypertension, according to results from the PATHWAY-2 study. This summary also includes details from the NICE 2011 hypertension guidelines.
A major study funded by the National Institute for Health Research concludes that more frequent lipid monitoring strategies are cost-effective when compared with other longer interval strategies to guide treatment for prevention of cardiovascular disease.
Results from the ADVANCE trial support the need for intensive efforts to promote smoking cessation in people with diabetes. As well as increased risks to cardiovascular health in all diabetic patients who smoke, women with diabetes who smoke appear to be at a greater risk of coronary events than men.
Professor Mike Kirby examines the evidence for the benefits of the NHS Health Check following a recent editorial casting doubts on the programme. Other emerging evidence suggests that the programme helps to reduce health inequalities and is effective at case finding for major physiological risk factors such as hypertension and diabetes.
Women with diabetes appear to be at a higher risk of developing vascular dementia than men, according to the results of a major systematic review including >2 million people published in Diabetes Care.